Cytogenetic and Cytotoxic Studies on the Effect of Phytoinvestigated Active Compounds of Hyoscyamus niger (in vivo and ex vivo)
This study included the reveal of the Cytogenetic effects of 6- Thioguanine and methotrexate in lymphocytes obtained from bladder cancer patients, in which we study the effects of those drugs on the blood samples obtained from patients and apparently health individuals, the patients were diagnosed in Al- Yarmouk Hospital.
In this study Mitotic index, blastogenic index, chromosomal aberrations, and micronucleus, were employed in the present study as cytogenetic parameters for the mentioned drugs. The most prominent findings of the present work were: