M.Sc.

                Oxymetazoline hydrochloride ion selective electrodes were constructed. Construction was based on drug complex formation with dodeca-tungstophosphoric acid as ionophor and many plasticizer: Di –butyl phthalate (DBPH), Tri- butyl phosphate (TBP), O- nitrophenyloctylether (ONPOE),  Di- octyl phthatale (DOP) in PVC matrix membranes. The matrix membrane was formed by mixing plasticizer and drug complexes with PVC.

          Three new ligands have been prepared in this work, which were chosen to synthesis a new set of transition metal complexes [Cu (II), Ni (II), Hg (II), Cd (II) and Co (II)]  LI=(2-[5-phenyl-2-methylthio-1,3,4-oxadizole]-5-phenyl-1,3,4-oxadiazole), LII=2-(O-chloro benzylidine) hydrazine benzothiazole and LIII=2-(p-hydroxy benzylidine) hydrazine benzothiazole were prepared by Schiff reaction between 2-mercaptobenzothiazole and 2-chlorobenzaldehyde and p-hydroxy  benzaldehyde.The new ligands were characterized by the Infra-red spectrosco