College of Science

1-In this study, some organic compounds contain hetero-atoms were synthesized by several steps as following:
 First; 4-phenylazoaniline [1] and 4-phenyl azophenol [17] were prepared in two steps:  
 The treatment of a primary aromatic amine (aniline) with nitrous acid to form a diazonium salt. Coupling reaction of aromatic diazonium ion with activated aromatic ring (aniline, phenol).

          Five transition metal complexes of Ni(II), Cu(II), Zn(II), Cd(II) and Sn(II) with {4-amino-5-(pyridyl)-4H-1,2,4-triazole-3-thiol}, as a ligand (L) has been prepared in alcoholic medium.
These complexes are:
1.  Bis(4-amino-5-(pyridyl)-4H-1,2,4-triazole-3-thiol) Nickel(II), Ni(L)
.
2.  Bis(4-amino-5-(pyridyl)-4H-1,2,4-triazole-3-thiol) Cupper(II), Cu(L)
.
3.  Bis(4-amino-5-(pyridyl)-4H-1,2,4-triazole-3-thiol) Zinc(II), Zn(L)
.
4.  Bis(4-amino-5-(pyridyl)-4H-1,2,4-triazole-3-thiol) Cadmium(II), Cd(L)
.

       This piece of research includes constructing and characterizing two kinds of ion-selective electrodes (ISEs) based on PVC matrix membrane.First, four ion-selective electrodes for clarithromycin (CLM) which based on clarithromycin-tetraphenylborate (CLM-TPB) ion-pair complex as the electro-active materials were prepared. Second, four ion-selective electrodes for clarithromycin which based on using clarithromycintetraiodomercurate (CLM-TIM) ion-pair complex as the electro-active materials were also prepared.