Effect of Carboxymethyl Nanochitosan Loaded with Streptomycin on Staphylococcus aureus and Pseudomonas aeruginosa
This study aimed to synthesise carboxymethylnanochitosn as nanochitosan derivative from nanochitosan synthesized from soluble chitosan (low molecular weight) and encapsulate streptomycin then characterize and bioassay them on pathogenic gram positive and gram negative bacteria and Rhabdomyosarcoma cell- line. Ionic gelation method was used to synthesize nanchitosan from soluble and insoluble chitosan (high molecular weight). Dissolved chitosan was found to be superior to non-soluble in the preparation of nanochitosan.