Biotechnology - Sciene

Genetic Polymorphism in MTHFR and PCO genes associated with the incidence of Polycystic Ovary Syndrome in A sample of Iraqi Women

    This study was constructed to investigate Polycystic ovary syndrome (PCOS) related infertility through a biochemical and molecular base associated with single nucleotide polymorphism (SNP) at methylene tetrahydrofolate reductase (MTHFR) gene and Poly cystic ovary (PCO) gene in Polycystic ovary syndrome (PCOS) Patients. The study included fifty blood samples of patients women suffering from Polycystic ovary syndrome (PCOS) during the period from November 2015 to January 2016, collected from Kamal al-Samarrai Hospital in Baghdad governorate.

English

Production, Purification, Characterization of Antibiotic from Locally Isolated of Actinomycetes spp. and Studying its Cytotoxicity and Antitumor Activity

Recently, the increase of the pathogens resistant to recent antimicrobial agents has become a health problem. Accordingly, the current study aimed at the isolation of local actinomycetes spp. that is capable of producing novel bioactive compounds, as well as investigating their biological (antimicrobial and anticancer) activities, in addition to, characterizing and partial purifiying the antimicrobials  metabolites. Forty soil samples were collected in Garmian area,during the period from 2 nd  to 15 th Feb. 2015.

English

Detection of Estrogen Receptor Alpha and Beta Gene Mutations in Iraqi Women with Breast Cancer

   This study was aimed to determine the mutations and single nucleotide polymorphisms (SNPs) in exon 4 and 6 of estrogen receptor alpha (ESR1) gene as well as exon 3 and 7 of estrogen receptor beta (ESR2) gene in Iraqi women with breast cancer. Different group of samples (25 of blood with FFPE from the same patient, 15 of fresh tissue with blood and FFPE from the same patient, and formalin fixed

English