M.Sc.

Synthesis of inorganic complexes derived from 4amino-5-(pyridyl)-4H 1,2,4 triazole-3-thiol and study their photochemical stability with polystyrene

          Five transition metal complexes of Ni(II), Cu(II), Zn(II), Cd(II) and Sn(II) with {4-amino-5-(pyridyl)-4H-1,2,4-triazole-3-thiol}, as a ligand (L) has been prepared in alcoholic medium.
These complexes are:
1.  Bis(4-amino-5-(pyridyl)-4H-1,2,4-triazole-3-thiol) Nickel(II), Ni(L)
.
2.  Bis(4-amino-5-(pyridyl)-4H-1,2,4-triazole-3-thiol) Cupper(II), Cu(L)
.
3.  Bis(4-amino-5-(pyridyl)-4H-1,2,4-triazole-3-thiol) Zinc(II), Zn(L)
.
4.  Bis(4-amino-5-(pyridyl)-4H-1,2,4-triazole-3-thiol) Cadmium(II), Cd(L)
.

English

Construction and study of new polymeric membrane electrodes for clarithromycin determination

       This piece of research includes constructing and characterizing two kinds of ion-selective electrodes (ISEs) based on PVC matrix membrane.First, four ion-selective electrodes for clarithromycin (CLM) which based on clarithromycin-tetraphenylborate (CLM-TPB) ion-pair complex as the electro-active materials were prepared. Second, four ion-selective electrodes for clarithromycin which based on using clarithromycintetraiodomercurate (CLM-TIM) ion-pair complex as the electro-active materials were also prepared.

English

SYNTHESIS, CHARACTERIZATION AND EVALUATION OF BIOLOGICAL ACTIVITY FOR SOME FIVE MEMBERED AND FUSED HETEROCYCLIC DERIVATIVES

In this study, some of five membered and fused heterocyclic derivatives containing 1,2,4- Triazole, 1,3,4- Thiadiazole and triazolo [3,4-b] thiadiazine were synthesized by several cyclization steps.2, 5-dimercapto-1, 3, 4-thiadiazole [A1] was obtained by the reaction of hydrazine hydrate with   carbon disulfide. Compound [A1] was reacted with Ethyl chloro acetate in presence of alkali ethanol to give 2, 5-bis (thioethylacetate 2, 2', diyl)1,3,4 thiadiazole [A2].

English