Thesis
Separation and detection of some cations by unsuppressed conductivity and indirect photometric methods
Cation exchange chromatography with both unsuppressed conductivity detection and indirect photometric (IPD) modes were used for the separation and detection of inorganic cations. Salt of weak base diphenylamine has been used as an eluent for several cations both with unsuppressed conductivity detection and IPD.
Synthesis and Characterization of Liquid Crystalline Materials as Stationary Phases In Gas ─Liquid Chromatography
This thesis consists of the synthesis of new liquid crystalline compounds 2-thiobutanoyl-5-[4-(4´-methoxybenzylideneamino)phenyl]1,3,4-oxadiazole 1e, 4-[4´-methoxyben- zylideneamion)benzoyloxy]propylbenzoate 2d and two new homologous series derived from 2,5-bis-[4-amino phenyl]-1,3,4-oxadiazole 3d, these are 2,5-bis-[4-(4´-alkoxybenzylideneamino)phenyl]-1,3,4-xadiazole 3e1-3i1 and 2,5-bis-[4-(4´-alkoxybenzanilide)phenyl]-1,3,4-oxadiazole 3e2-3i2.(3e2,f2,g2,h2, i2
Synthesis and characterization of mono- and poly-nuclear complexes of dithiocarbamate derivative of 2-amino-5-mercapto-1,3,4-thiadiazole
Derivatives of 1,3,4-thiadiazole ring show biological activities against different species of microbes, therefore mono- and poly-nuclear complexes of dithiocarbamate derivatives of 2-amino-5-mercapto-1,3,4-thiadiazole (AMT), have been prepared in an attempt to show the effect of introducing two centers in the structure of the ligand (NaMTD), as well as to investigate the coordination behavior of the ligand toward both transition metals and to compare the biological activity of the complexes with that of the ligand.Dithiocarbamate derivatives of AMT (NaMTD), were
Synthesis of New Heterocyclic Compounds derived from 2-Amino-5-Mercapto-1,3,4-Thiadaiazole
The scheme of this work involves synthesis of different heterocyclic rings utilizing the two different reactive sites of 2-amino-5-mercapto-1,3,4-thiadiazole.This work is divided into four different parts:
First Part: Involved synthesizing two new fused rings derived from the reaction of –NH2 group of the starting material with different organic reagents. The following reaction steps shown in scheme [I] are of a feasible strategy:
SYNTHESIS, LIQUID CRYSTALLINE PROPERTIES, AND BIOLOGICAL ACTIVITY OF SOME NOVEL TRIS-SCHIFF’S BASES CONTAINING 1,3,4-THIADIAZOLE RING SYSTEM
The present work consists of four parts. The first part deals with the synthesis of new series 1,3,5-tri-[5(4’-n-alkoxyphenyl)-1,3,4-thiadiazol-2-yl-]-trimesilydene [7]n, involving four steps which were outlined as follows:Step one: Preparation of 4-n-alkoxybenzoic acid[2]n
The reaction of 4-hydroxybenzoic [1] acid with different n-alkyl halides afforded the corresponding 4-n-alkoxybenzoic acid[2]n. Step two: Synthesis of 2-amino-5-(4-n-alkoxyphenyl)-1,3,4-thiadiazole[3]n
Synthesis of New Heterocyclic Compounds Via Nitrile group
Preparation of new derivatives of heterocyclic compounds such as (Triazoles, teterazoles ,oxazoles,thiadiazoles,oxadiazoles and oxazolones) were the aim of this work .This work was achieved through the prepration of α- aminonitrile, which was prepared using amodified streck's procedure it incloud the reaction of amine (p-anisidine) with approprte aldehyde (benzaldehyde) followed by the addition potassium cyaide.The reaction was carried at PH(3-4) using glacial acetic acid as solvent.Hydrolysis of the α-aminonitrite with 90% sulpheric ac
Synthesis of Heterocyclic Derivatives of N- Substituted Phenothiazine
The aim of the present work is the synthesis of new derivatives of N-substituted 10H phenothiazine.To obtain these derivatives, the diphenylamine was chosen as the starting material which was heated for 5hrs. with sulfur in presences of iodine, it gave the phenothiazine (1).1- Reaction of phenothiazine with chloro acetyl chloride gave N10- (chloro acetyl) phenothiazine (2), which was treated with hydrazine hydrate to give N10- (acetyl phenothiazine) hydrazine (3) which is the desired product.
Separation and detection of some anions by Ion Chromatography using indirect photometric and conductivity methods
Anion exchange chromatography with both indirect photometric detection (IPD) and unsuppressed conductivity detection modes were used for the separation and detection of inorganic anions. Salt of phthalic acid has been used as an eluent for several anions both with IPD and conductivity detection.
Biochemical Study of some derivatives of L-Ascorbic acid as a pro-drug
In this work new derivatives of L-ascorbic acid (Vitamin C ) have been stynthezized .