Chemistry - Sciene

The present work includes the synthesis of different Schiff’s bases [3(A-C)] by the reaction of 2-Aminopyridine [2] with benzaldehyde and its derivatives   [1(A-C)]. These Schiff’s bases react with benzoyl chloride [4] to yield benzamide derivatives [5(A-C)]. The synthesis of L-amino acid derivatives [6(A-C)–10(A-C)] has been performed by the reaction of benzamide derivatives [5(A-C)] with (Glycine, L-Alanine, L-Phenylalanine, L-Asparatic acid and  L-Asparagine).

This study involves the preparations of some pyridine derivatives starting from  Isonicotinic acid (1) following these steps :First : The Synthesis of  Isonicotinoyl acid chloride (2) by The  reaction of Isonicotinic acid (1) and thionylchloride .Second : The Synthesis of some amide and ester derivatives by reaction between  Isonicotinoyl acid chloride (2) and substituent amine or phenol derivatives ( Semicarbazide, Thiosemicarbazide, Benzohydrazide, Aniline, 4-phenylazoaniline, 4-phenylazophenol, p-Aminophenol, p-Aminoacetophenone, m-Toluidine, 4-Bromoaniline )

Room temperature ionic liquids gained massive growth in recent years for their distinguished characterization like non-volatile and designed media for variable chemical and industrial application. In addition, indium metal has applications in electronic and optoelectronic devices, tin and antimony metals have good corrosion resistance and optical properties respectively.