This work involves synthesis of different five and six member heterocyclic rings starting from phenyl acetic acid. This work is divided into four different parts:
First part:
This part involved the synthesis of phthalazin-3,8-dione [7] and pyridazin-3,6-dione [6], pyrazole [4,5] and thiadiazole[8] derivative derived from phenyl acetyl hydrazide[3] . as shown in scheme I.
Second part:
This study concened with the study of solute-solvent interaction of vitamins:[Ascorbic Acid,pantothenic Acid,Folic acid,Thiamine and Pyridoxne] as solutes in water and in hydrochloric acid solution (0.1 mol.L 1) as solvents This study coverd experimental measurements using Anton Paar (DMA 60/602) densimeter, as well as theoretical caculatoins concerning partial molal volume, and some related parameters,a comparison and discussion was made in the light of these mesurements.
Chemotherapy is the science of selective toxicity. The goal of chemotherapeutic treatement is to selectively attenuate or destrory pathogenic microorganisms or cells with minimal side effects to the host . These target cells or organisms may be bacteria , viruses , fungi , or tumor cells .
