This research is divided into two parts:
Part one:
This part involved in the synthesis of some pyrimidine derivatives which play an important role in the medicinal chemistry because they possess promising cytotoxic activity.The synthesized compounds:
New stationary phase for high performance liquid chromatography has been prepared by the interaction of crystal violet solution with silica gel.The stability of the new attached functional group on the new stationary phase was studied against different solvents such as benzene, ethanol,acetonitrile, acetone, methanol, hexane, chloroform, and petroleum ether as well as NaOH and HCl solutions.
This work involved the use of UV-VIS spectrophotometric and spectrofluorometer to study the photoproperties and the determination of riboflavin in the vitamin synthetic standards either directly from the
