PhD

Biomedical inorganic chemistry offers the potential for the design novel therapeutic agents for the treatment of diseases, which are currently intractable.Therapeutic metalodrugs have since long been employed to restore human physiology.

1. preparation of thiazolidene-4-none (2) , imidazolidine-4-ones (3) , and oxazepine-4,7-diones (4) from schiff bases (1) by reaction with 2-mercaptoacetic acid ,glycine and malic anhydride respectively .
2. preparation of 1-phenyl-3-hetero-2-yl urea and thiourea from reaction of hetero amines with phenylisocyanate and phenylisothiocyanate respectively .

Novel series of 14 (urea and thiourea) derivative compounds were prepared from reaction of urea and thiourea with aromatic amine compounds (homocyclic and heterocyclic), in addition to preparation of 6 Schiff bases (C=N) compounds that were prepared from reaction of some derived compounds with benzyldehyde in this study. All the 20 prepared compounds were characterized according to F.T.I.R.