M.Sc.

      Cephalexin is a medical drug administrated commonly for the treatment of infections.Two methods were examined for determination of cephalexin based on conventional and derivative UV absorption spectrophotometry.The calibration curve at 262 nm has linear range extended from (1.5-100) ppm with relative standard deviations for the slope of 0.91 and correlation coefficient of 0.9993. The effect of pH on the determination of cephalexin at this wavelength was also investigated.

The work in this thesis involves three parts.Part I: Synthesis:

Acridone derivatives containing 1, 3, 4-oxadiazole and 1, 3, 4-thiadiazole rings are synthesized according to the following steps:

This study represents a small contribution to draw attention towards the water quality with respect to the amount of the metal ions (calcium, magnesium, chloride, copper, iron and lead) in some Iraqi water resources (tap, river and ground water).