SYNTHESIS OF SOME NEW HETEROCYCLIC COMPOUNDS CONTAINING 9(10H)-ACRIDONE, AND STUDYING THEIR BIOLOGICAL ACTIVITY

number: 
1344
English
department: 
Degree: 
Author: 
Ayad Kareem Khan Bawa
Supervisor: 
Dr. Ayad S. Hameed
year: 
2006

The work in this thesis involves three parts.Part I: Synthesis:

Acridone derivatives containing 1, 3, 4-oxadiazole and 1, 3, 4-thiadiazole rings are synthesized according to the following steps:

Step one: Diphenylamine-2,4`-dicarboxylic acid [1] is obtained in a high yield by refluxing a mixture of 4-aminobenzoic acid and 2-chloro benzoic acid in the presence of catalytic amount of copper oxide.