M.Sc.

This research is divided into two parts:
  Part one:
This part involved in the synthesis of some sulfa drugs which play an important role in the medicinal chemistry because of their antibacterial activity.The synthesized compounds:
1.p-Amino-N-(2-methylphenyl)benzene Sulfonamides.
2.p-Amino-N-(2-methoxyphenyl)benzene Sulfonamides.
3. p-Amino-N-(4-chlorophenyl)benzene Sulfonamides.
4. 4-(Morpholinosulfonyl) aniline.
5. 4-(Piperidin-1-yl sulfonyl) aniline.

New Schiff's bases with 1,2,4-triazole ring (3a-j) have been synthesized from 4-(4'-amino-5-mercapto-4H-1, 2, 4-triazol-3-yl) phenol (2) which is obtained from 4-hydroxybenzohydrazide (1) by a cyclization reaction as shown in (scheme 3-1). Infrared spectroscopy and ¹H NMR spectroscopy were used to characterize the structures of synthesized compounds.

This piece of research includes three  main  chapters .Chapter one  includes an  introduction on  ion selective electrodes (ISEs) and their work, properties, classification of ion selective membranes, cell design of ion-selective electrode and characterization of ion-selective electrodes such as  selectivity coefficient with different method (separation solution method) and (matched potential method)with  range   of linear response,detection limit, response of time.Molecularly imprinted polymers (MIP) Technique and Approaches for preparing Molecularly Imprinted Polymers (Covalent Imprinting