Synthesis and biological activity of five, six and seven membered heterocyclic derivativese.+CD
English
College of Science
Synthesis and biological activity studies of new 1,2-diazin-dione,1,3,4-oxadiazole, 4-oxazoline, 4-thiazolidinone and 1,3-oxazepin-dione derivatives. +CD
Abstract:
The scheme of this work involves synthesis of new five, six and seven membered heterocyclic rings derived from p-Toluic acid [1].This work is divided into four parts: -Part one: - Include synthesizing phthalazin, pyridazin-dione and oxadiazole derivatives [4], [5], [6] and [7] derived from 4-methyl benzoic hydrazide [3] which was prepared from the reaction of ethyl-4-methyl benzoate [2] with hydrazine hydrate as show in scheme 1.
English
Synthesis of some new 1,3,4-oxadiazole compounds and its inhibitory effect on S.aureus and E.coli. +CD
English