College of Science

The synthesized compounds were characterized using FTIR, 1HNMR 13CNMR, EI-Mass spectroscopy and CHN analysis. The liquid crystalline properties of the prepared compounds which were verified using differential scanning calorimete (DSC) and hot-stage polarizing optical microscope (POM) were discussed. The

This research is divided into two parts: Part one: This part involved in the synthesis of some pyrimidine derivativeswhich play an important role in the medicinal chemistry because they possess promising cytotoxic activity. The synthesized compounds: 1. 5,6-diaminouracil-2,4-diol hydrochloride. 2.5,6-diamino- 2-mercaptopyrimidine-4-ol hydrochloride. 3.2-mercapto-6-methylpyrimidin-4(3H)-one. 4.2-hydrazinyl-6-methylpyrimidin-4(3H)-one 5.2-(2-(4-(dimethylamino)benzylidene)hydrazinyl)-6-methylpyrimidin-4(3H)-one.