Studying the effect of Lactobacillus acidophilus on the pathological effect of Proteus mirabilis in mice
Proteus mirabilis, a common cause of nosocomial and catheter associated urinary tract infection, colonize the bladder and ascends the ureters to the proximal tubules of kidneys, leading to the development of acute pyelonephritis (Angela et al., 2003). Adherence of P. mirabilis to uroepithelial tissue may be an important virulence determinant in these infections because most proteus strains adhere to desquamated uroepithelial cells (Susan et al., 1986). Also p.