Detection of Mutations in Exon 10 and 13 of ATP7B Gene among Iraqi patients with Wilson Disease
copper metabolism due to mutations in copper transport gene ATP7B resulting in hepatic and neuropsychiatric manifestation. The aim of this study is to investigate the extent to which mutations in gene ATP7B involved in development of WD and assessment of parameters related to copper metabolism in patients with Wilson disease. Accordingly, blood samples were obtained from 35 patients with WD (20 male and 15 female) with a mean age of 9.12 years and age range of 5 – 40 years old Other 10 apparently, healthy individuals were also included.