College of Science

Detection of Mutations in Exon 10 and 13 of ATP7B Gene among Iraqi patients with Wilson Disease

copper metabolism due to mutations in copper transport gene ATP7B resulting in hepatic and neuropsychiatric manifestation. The aim of this study is to investigate the extent to which mutations in gene ATP7B involved in development of WD and assessment of parameters related to copper metabolism in patients with Wilson disease. Accordingly, blood samples were obtained from 35 patients with WD (20 male and 15 female) with a mean age of 9.12 years and age range of 5 – 40 years old Other 10 apparently, healthy individuals were also included.

English

Genetic Polymorphism in MTHFR and PCO genes associated with the incidence of Polycystic Ovary Syndrome in A sample of Iraqi Women

    This study was constructed to investigate Polycystic ovary syndrome (PCOS) related infertility through a biochemical and molecular base associated with single nucleotide polymorphism (SNP) at methylene tetrahydrofolate reductase (MTHFR) gene and Poly cystic ovary (PCO) gene in Polycystic ovary syndrome (PCOS) Patients. The study included fifty blood samples of patients women suffering from Polycystic ovary syndrome (PCOS) during the period from November 2015 to January 2016, collected from Kamal al-Samarrai Hospital in Baghdad governorate.

English

Production, Purification, Characterization of Antibiotic from Locally Isolated of Actinomycetes spp. and Studying its Cytotoxicity and Antitumor Activity

Recently, the increase of the pathogens resistant to recent antimicrobial agents has become a health problem. Accordingly, the current study aimed at the isolation of local actinomycetes spp. that is capable of producing novel bioactive compounds, as well as investigating their biological (antimicrobial and anticancer) activities, in addition to, characterizing and partial purifiying the antimicrobials  metabolites. Forty soil samples were collected in Garmian area,during the period from 2 nd  to 15 th Feb. 2015.

English