College of Medicine

The term apoptosis can be defined as a morphologically distinctive form of cell death which was associated with normal physiology. The apoptotic cell exhibit a number of distinctive morphological and biochemical changes including membrane bleb formation followed by condensation of cytoplasm and nuclear chromatin condensation into uniformly dense masses near the nuclear envelope with DNA fragmentation. Finally,the

Clindamycin LD50 value against L.donovani promastigotes (1.07mg/ml) was more potent than control in opposite axenic and intramacrophage amastigotes (0.07 and 0.15 mg/ml) was less potent than control respectively, against L.major promastigotes, axenic and intramacrophage amastigotes (1.0, 0.015 and 0.64 mg/ml) was less potent than control respectively and against L.tropica promastigotes, axenic and intramacrophage amastigotes (0.63, 0.21 and 0.53 mg/ml) was less potent than control respectively.