Tissue Culture of Mice Bone Marrow Mesenchymal Stem Cells Differentiation to Motor Neural cell

   Stem cells are relatively unspecialized cells that have the ability to renew themselves and produce a variety of specialized cells after division without limit, as long as animal is still alive. These criteria were directed to produce many types of differentiated cells to repair damage in the body (Watt , 2011). It is the original cell of an organism that has the ability to develop into many different types of cells in the body. Stem cells serve as a source of internal repair system; divide mainly without limit to replace other cells as long as the organism is alive. When divided, each cell has the potential to remain a stem cell or become one type of specialized like red blood cell or a brain cell (Hongbao  et al.,2015).  Stem cells are divided on the base of their potency into totipotent, pluripotent ,multipotent, oligopotent and unipotend regarding their division ability and according to their source where they derive to embryonic, fetal, adult, amoniatic fluid,  cord blood and induce pluripotent stem cell (Dubie, et al., 2014).  Pluripotent stem cells are distributed into two categories, endogenous pluripotent  stem cells found during development that divide into embryonic stem cells (ESCs) and postnatal (“adult”) stem cells (ASCs) and reprogrammed
Pluripotent stem cells derived by either somatic cell nuclear transfer (SCNT) or insertion of specific genes into terminally differentiated cells (Young and Black, 2014)