Since Central Asia states independence, Iran attempts to replace the ideology of communism by the religious one in its and to lay the foundations for that. Iran is motivated by the Muslim majority of the states which some are culturally related such as Tajikistan and part of Uzbekistan and some are connected by their sect such as Azerbaijan. Besides, the disintegration of the Soviet Union as much as exempts Iran from certain security obligations, it allows Iran to avoid security and political disruptions, for example, the accession of the Iranian-Azerbaijani Popular National Front to power in the mid of 1992 and its clear call for the independence of Iranian Azerbaijan and the formation of the Great Azerbaijani State. Also, Iran's insistence on owning weapons capability, planning to be the largest military force in the region, is encouraged by the need of the Central Asia states for foreign currency and the arrangement of transactions which enable Iran to have weapons and nuclear technology and metals. It is no doubt that the Central Asian states, which have an important wealth, are considered a vital area of the economy of Iran which represents a trade route which is important for the landlocked countries. This brings back the historical vitality of Iran as being the trade rout that links the East to the West. This trade route is not limited to the overland, but it extends to include the adoption of the networks of oil and gas pipelines depending on the fact that Iran is the only link between the Caspian Sea and Persian Gulf. Iran achieved successes in its policy toward Asia, and its intervention in solving many problems, as is the case in (Nacorne Karabakh) after it has been able to persuade the two Armenian and Azeri agreeing to the truce and sit at the negotiating table. However there are several obstacles which affect the direction of Iran, such as its economic problems caused by the sanctions and Western pressure, including the internal political stability and the differences between secular and religious currents. There are also several external constraints like the existence of several regional and international roles which attempt to penetrate into those countries which through their work intersects with the Iranian role. The American role is the most important one in the region, particularly because it supports the role of Turkey and Israel at the expense of the Iranian role. This is reflected in the gains of Iran. In spite of the achievements of Iran in that region, they were not up to the ambition of Iran because of the existence of such constraints affecting the reality and the future of its orientation.