This work involves synthesis and biological activity of some amino and barbituric acid derivatives via shiff bases. This work is divided into six different parts:
Part One:
This part involved the synthesis of different shiff bases [1] by reaction of the aniline with benzaldehyde and its derivatives.
Part Two:
Hyperlipidemia is an elevated concentration of lipids in the blood. The major plasma lipids of interest are total cholesterol and the triglycerides. It is closely related to the terms hyperlipoproteinemia (elevated levels of lipoproteins).
Two cross linked polymers were synthesized, the first polymer was synthesized by condensation reaction between glycerol triethanol amine with maleic anhydride. The second polymer was synthesized by addition polymerization of free radical for acrylamide, bisacrylamide with ammonium persulphate and N,N,N,N-tetramethyldiamine (TEMED). The products were characterized by FTIR & X-ray. The resulted polymer have high rigidity and easily grinded, with high stability and used as stationary phase for HPLC.
