Biochemical Studies of the Binding of CA 19-9 to its Antibody in Patients with type 2 Diabetes Mellitus using Enzyme-Linked Immunosorbent Assay with some Modifications
Back ground:-
Back ground:-
This research is divided into two parts:
Part one:
This part involved in the synthesis of some sulfa drugs which play an important role in the medicinal chemistry because of their antibacterial activity.The synthesized compounds:
1.p-Amino-N-(2-methylphenyl)benzene Sulfonamides.
2.p-Amino-N-(2-methoxyphenyl)benzene Sulfonamides.
3. p-Amino-N-(4-chlorophenyl)benzene Sulfonamides.
4. 4-(Morpholinosulfonyl) aniline.
5. 4-(Piperidin-1-yl sulfonyl) aniline.
New Schiff's bases with 1,2,4-triazole ring (3a-j) have been synthesized from 4-(4'-amino-5-mercapto-4H-1, 2, 4-triazol-3-yl) phenol (2) which is obtained from 4-hydroxybenzohydrazide (1) by a cyclization reaction as shown in (scheme 3-1). Infrared spectroscopy and 1H NMR spectroscopy were used to characterize the structures of synthesized compounds.