Chemotherapy is the science of selective toxicity. The goal of chemotherapeutic treatement is to selectively attenuate or destrory pathogenic microorganisms or cells with minimal side effects to the host . These target cells or organisms may be bacteria , viruses , fungi , or tumor cells .
A new ligand have been prepared in this work, which was chosen to synthesis a new set of transition metal complexes [Mn(ІІ),Co (II), Ni (II),Cu(ІІ),Zn(ІІ),Hg (II),Cd (II),Pd(ІІ), Cr(ІІІ) and Rh (IІI)].
The new ligands have been prepared in this work (potassium 2carbomethoxy amino 5-5trithiocarbonate 1,3,4-thiadiazole ) (LI) was prepared from 2-carbomethoxy amino-5-mercapto 1,3,4-thiadiazole with CS2 in alkali media , while the second ligand was prepared from 2-N(4-N,N-dimethylamino benzyliden)-5-mercapto 1,3,4-thiadiazole with CS and in alkali media to obtain potassium 2-N( 4-N,N-dimethylaminobenzyliden )4-trithiocarbonate 1,3,4thiadiazole ( LII).The products were isolated and characterized by appropriate physical measurement , vibratio
