1. الرئيسية
  2. Thesis

Thesis

SYNTHESIS AND BIOLOGICAL ACTIVITY OF FIVE, SIX AND SEVEN MEMBERED HETEROCYCLIC DERIVATIVESE

          This work involves synthesis of different five, six and seven membered heterocyclic rings starting from 2-hydrazino benzothiazole which was synthesized from the corresponding 2-mercapto benzothiazole on its reaction with hydrazine hydrate. This work is divided into four different parts:

First part: This part involved the synthesis of oxadiazole, oxazoline, triazole, thiadiazole and diazole from compounds [a], [1] and [19] with different organic materials as shown in Schemes (1) and (2).

إنجليزية

Synthesis and Biological Activity Studies of New 1, 2-diazin-dione, 1, 3, 4-oxadiazole, ∆4-oxazoline, 4-thiazolidinone and 1, 3-oxazepin-dione derivatives

          The scheme of this work involves synthesis of new five, six and seven membered heterocyclic rings derived from p-Toluic acid [1].This work is divided into four parts: -Part one: - Include synthesizing phthalazin, pyridazin-dione and oxadiazole derivatives [4], [5], [6] and [7] derived from 4-methyl benzoic hydrazide [3] which was prepared from the reaction of ethyl-4-methyl benzoate [2] with hydrazine hydrate as show in scheme 1.intermolecular cyclization of semicarbazide derivatives [8], [9]  with 4-bromophenancyl bromide respectively

إنجليزية

Synthesis and antibacterial activity of some new heterocyclic compounds derived from p-bromobenzoic acid

         The scheme of this work involves synthesis of different five and six membered heterocyclic rings starting from 4-bromobenzoic hydrazide which was synthesized from their carboxylic acid.

          This work is divided into four different parts:

First part:

إنجليزية

Synthesis of Triazole, Thiadiazine, Pyrazole, Oxazoline, Oxadiazole, Oxazole, and Thiazole Derivatives and study The Biological activity for some of them

     The scheme of this work involves synthesis of different five and six membered heterocyclic rings starting from isonicotinic acid hydrazide and p-hydroxy methylbenzoate .This work is divided into seven different parts and the reaction steps for part are summarized in the comprehensive scheme.

First part:

إنجليزية

Synthesis of Triazole, Thiadiazine, Pyrazole, Oxazoline, Oxadiazole, Oxazole, and Thiazole Derivatives and study The Biological activity for some of them

     The scheme of this work involves synthesis of different five and six membered heterocyclic rings starting from isonicotinic acid hydrazide and p-hydroxy methylbenzoate .This work is divided into seven different parts and the reaction steps for part are summarized in the comprehensive scheme.

First part:

إنجليزية

Preparation and Potentiometric Study for Promethazine Hydrochloride Selective Electrodes and their Use in Determination of some Drugs

Electrodes for  the determination of promethazine hydrochloride based on PVC membrane were prepared based on the use of ion pair (promethazine-phosphotungstic acid) with the following plasticizers: Di-butyl phosphate (DBP), Tri-butyl phosphate (TBP), O-nitrophenyloctyl ether (ONPOE), and Di-butyl phthalate  (DBPH). The properties of these electrodes were studied, including: slope, correlation coefficient, concentration range, detection limit, pH effect, and life time.

إنجليزية

SYNTHESIS AND PHOTOSTABILITY STUDY OF SOME MODIFIED POLY(VINYL CHLORIDE) CONTAINING PENDANT BENZOTHIAZOLE AND BENZIMIDOZOLE RING

  The present work consist of two parts:-

Part one:-synthesis and characterization

 Five modified PVC polymers containing benzothiazole and benzimidazole as bending groups in the repeating units were synthesized in this work according to the following:

1-PAA: Reaction of PVC with 2-amino benzothiazole in THF solvent afforded the following modified polymer (PAA)

إنجليزية

SYNTHESIS OF SOME PYRIMIDINE DERIVATIVES AND STUDY THEIR ANTIBACTERIAL ACTIVITY

The current study involves the preparation of pyrimidine derivatives from reaction of thiopyrimidine with different compounds of hydrazine hydrate derivatives, amines and with ethylaceto acetate as in compounds:

1) 6-methyl-4-oxo-1,2,3,4-tetrahydro-2-thiopyrimidine.

2) 2-hydrazino-6-methylpyrimidine-4-(3H) one.

3)6-methyl-2-(3-methyl-5-oxo-4,5-dihyro-1-H-pyrazol-1-yl)-pyrimidine-4-(H) one.

4) 2-phenylhydrazino-6-methylpyrimidine-4-(3H) one.

5) 2-(2,4)-dinitrophenylhydrazino-6-methylpyrimidine-4-(3H) one.

إنجليزية

Preparation of some magnesium compounds as fuel additives

     The successful burning of heavy  fuel in gas turbines depends on the additive to prevent hot corrosion of hot gas path components, to prevent vanadium hot corrosion in the turbine hot gas path, a minimum ratio of magnesium to vanadium is required. In this work a number of oil-soluble and oil dispersible inhibitors were prepared to give a variety of magnesium complexes of different metal content and oil – solubility, these include;

إنجليزية
المزيد