Synthesis of some sulfa drug derivatives as antibacterial agents

This research is divided into two parts:
  Part one:
This part involved in the synthesis of some sulfa drugs which play an important role in the medicinal chemistry because of their antibacterial activity.The synthesized compounds:
1.p-Amino-N-(2-methylphenyl)benzene Sulfonamides.
2.p-Amino-N-(2-methoxyphenyl)benzene Sulfonamides.
3. p-Amino-N-(4-chlorophenyl)benzene Sulfonamides.
4. 4-(Morpholinosulfonyl) aniline.
5. 4-(Piperidin-1-yl sulfonyl) aniline.
Sulfa drug compounds were identified by using elemental analysis, FTIR spectroscopy, UV-Visible spectroscopy and by measuring their melting points.
Part two:
This part involved the activity of the synthesized sulfa compounds on different pathogenic bacteria(staphylococcus aureus and pseudomonas aeruginosa) in vitro by using well diffusion method, different
concentrations of sulfa drugs were prepared. Some compounds showed an inhibitory effect on the growth of the two bacteria and the others showed no inhibition activity.