Study the Effect of Aromatase Inhibition in Postmenopausal Breast Cancer Patients and Its Cytotoxic Effect In-Vitro

Background:
Hormone therapy is the first targeted therapy also called estrogen suppression therapy often used as an adjuvant therapy to reduce the risk of cancer back after surgery or cancer that has spread. Aromatase inhibitors such as Present study was planned to assess the effect of anastrozole on aromatization mechanism According to aromatase enzyme activity and estradiol level. As well, study the cytotoxic effect of anastrozole on three types of cell line