Serum total and lipid association sialic acid levels in diabetic and hypertensive patients.

number: 
875
إنجليزية
department: 
Degree: 
Imprint: 
Chemistry
Author: 
Hiba Ali Hassan Al-Habeeb
Supervisor: 
Dr.Nazar A. Naji
Dr.Hashim M. Hashim
year: 
2004
Abstract:

In this study serum total sialic acid, lipid associated sialic acid, urea and uric acid levels -were estimated in 123 patients and compared with 20 comparable age and sex healthy controls. The samples were collected from the University Teaching Hospital/Iraqi College of Medicine. The patients were divided into five groups: - 4 Patients with insulin dependent diabetes. Patients with non-insulin dependent diabetes. Patients with hypertension. dependent-hypertension. 4 Patients with non-insulin Patients with insulin dependent-hypertension. Serum total sialic acid, lipid association sialic acid, urea and uric acid were determined by using spectrophotometric analysis. The results in this study showed: A significantly increase at (P<0.05) in serum TSA levels in IDDM patients and NIDDM-HT patients, highly significant increase at (P<0.001) in HTpatients, N1DDM patients and IDDM-HTpatients as compared with healthy controls. 4 A highly significant increase at (P<0.001) in serum LSA levels in all patients as compared with healthy controls. 4 A significantly increase at (P<0.05) in male serum uric acid levels in IDDM patients and IDDM-HT patients, highly significant increase at (P<0.001) in HT patients, non significant increase at (P>0.05) in NIDDMpatients and NIDDM-HT patients as compared with healthy controls. 4 A significant increase in female serum uric acid levels in IDDM patients, NIDDM patients and IDDM-HT patients, highly significant increase at (P<0.001) in HT patients and NIDDM-HT patients as compared with healthy controls. 4 A highly significant increase at (P<0.001) in serum urea in all patients as compared with healthy controls.