Chemistry - Sciene

This study is concerned with the synthesis and characterization of some new liquid crystalline compounds derived from di- and tri-hydroxy benzoic acids with bis-swallow tailed which called N,N`-1,4-phenyl-bis[3`,5`-disubstituted benzamide] , N,N`-4,4`-biphenyl-bis[3``,5``-disubstitutedbenzamide], N,N`-1,4-phenyl-bis[3`,4`,5`-trisubstitutedbenzamide] and N,N`-4,4`-biphenyl-bis[3``,4``,5``-tri substituted benzamide] which were synthesized according to the following schemes(1, 2, 3, 4):

In recent years the computational chemistry becomes of great importance in many chemical and pharmaceutical scientific fields. Since many of the oxadiazole derivatives have a wide range in biological, and pharmacological activities.Therefore this work involves a theoretical study for two series of oxadiazole derivatives.

   Three new antibacterial ligands have been prepared in this work by the reaction of 6-amino penicillanic acid (6-APA) with terephthaladehyde, glyoxal and vanillin to produce L1, L2and L respectively.