A Comparative study between thyroid hormones and lipid profile in diabetes Type 2

number: 
3724
إنجليزية
Degree: 
Author: 
Noor Asaad Abood Al-Mtoori
Supervisor: 
Dr. Asmaa Ali Hussein
year: 
2016

          This study focused on the survey of thyroid abnormalities symptoms (hypo and hyperthyroidism) and estimating the level of these hormones free tri-iodothyronine (FT3), free tetra-iodothroxine (FT4) and thyroid stimulating hormone (TSH) among type 2 diabetic Iraqi patients. Also the lipid profile triglyceride (TG), total cholesterol (TC),  high density lipoprotein (HDL), low density lipoprotein (LDL) and very low density lipoprotein (VLDL) levels for these diabetic patients were compared with non diabetic healthy group. Ninety Cases in this study were consist of thirty diabetic patients with hypothyroidism and another
thirty diabetic patients with hyperthyroidism. Thirty blood samples from healthy non diabetic and non endocrine disease people were chosen as controls. Complete information includes: history of diabetes, age, sex,  length, weight, body mass index and any other disease were taken for each case under study. The result showed high incidence of abnormal thyroid hormones level were observed in type 2 diabetic patients, where the level of FT3 in diabetic patients with hyperthyroidism was(5.35  ) µL/mL, while in diabetic patients with hypothyroidism was (4.48) µL/mL compared with healthy control (5.79) µL/mL. The level of FT4 in diabetic patients with hyper and hypothyroidism (14.94, 15.08) µL/mL respectively, compared with healthy control (15.07) µL/mL. While the level of TSH in diabetic patients with hyper and hypothyroidism (0.96,7.21 µ) L/mL respectively, compared with healthy control (1.88)  µL/mL . Also the results of statistical analysis showed a significant correlation in at least  at  P<0.05 between total cholesterol, triglyceride with FT3 and TSH in hypo and hyperthyroidism. On the other hand, the results showed a significant correlation  at P<0.05 in age and  body mass index in diabetic patients when compared with  control group. Also statistical analysis showed that thyroid disorders were more prevalent in female than male.